Retrospective Cohort Study
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Feb 16, 2020; 12(2): 72-82
Published online Feb 16, 2020. doi: 10.4253/wjge.v12.i2.72
Endoscopic treatment modalities and outcomes in nonvariceal upper gastrointestinal bleeding
Benjamin Cherng Hann Yip, Hossain Sayeed Sajjad, Jie-Xun Wang, Constantinos P Anastassiades
Benjamin Cherng Hann Yip, Constantinos P Anastassiades, Department of General Medicine, Khoo Teck Puat Hospital, Singapore 768828, Singapore
Hossain Sayeed Sajjad, Department of Acute Medicine, Northampton General Hospital, Cliftonville, Northampton NN1 5BD, United Kingdom
Jie-Xun Wang, Clinical Research Unit, Khoo Teck Puat Hospital, Singapore 768828, Singapore
Author contributions: All the authors contributed equally in data extraction, data analysis and writing of the paper.
Institutional review board statement: The study was reviewed and approved for publication by our Institutional Reviewer-NHG Domain Specific Review Board.
Informed consent statement: A waiver of informed consent has been obtained from our institution ethics review board.
Conflict-of-interest statement: All the Authors have no conflict of interest related to the manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Benjamin Cherng Hann Yip, MBBS, MRCP, Doctor, Department of General Medicine, Khoo Teck Puat Hospital, 90 Yishun Central, Singapore 768828, Singapore. yip.benjamin.ch@ktph.com.sg
Received: June 18, 2019
Peer-review started: June 23, 2019
First decision: August 2, 2019
Revised: November 25, 2019
Accepted: December 14, 2019
Article in press: December 14, 2019
Published online: February 16, 2020
Core Tip

Core tip: This is the first study to our knowledge attempting to demonstrate a dose-response relationship between the commonly used endoscopic modalities for the treatment of non-variceal upper gastrointestinal bleeding and various clinical outcomes. Ours is also the first study to show that a greater number of hemoclips deployed led to a better outcome. It is a real-world study and results were generated from patient care in daily clinical practice.