Copyright
©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Oct 16, 2018; 10(10): 301-307
Published online Oct 16, 2018. doi: 10.4253/wjge.v10.i10.301
Published online Oct 16, 2018. doi: 10.4253/wjge.v10.i10.301
Yield of capsule endoscopy in obscure gastrointestinal bleeding: A comparative study between premenopausal and menopausal women
João Carlos Silva, Rolando Pinho, Adélia Rodrigues, Ana Ponte, Jaime Pereira Rodrigues, Mafalda Sousa, Catarina Gomes, João Carvalho, Department of Gastroenterology, Centro Hospitalar Vila Nova de Gaia/Espinho, Porto 4434-502, Portugal
Author contributions: Silva JC and Pinho R designed the study, performed the research, analyzed the data and wrote the paper; Rodrigues A, Ponte A, Rodrigues JP, Sousa M, Gomes C and Carvalho J performed the research and analyzed the data.
Institutional review board statement: The study was reviewed and approved by the review board of Centro Hospital de Vila Nova de Gaia/Espinho.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare no conflict of interest for this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: João Carlos Silva, MD, Doctor, Department of Gastroenterology, Centro Hospitalar Vila Nova de Gaia/Espinho, Rua Conceição Fernandes, Vila Nova de Gaia, Porto 4434-502, Portugal. joaocarosilva@gmail.com
Telephone: +351-22-7865100 Fax: +351-22-7868369
Received: April 30, 2018
Peer-review started: April 30, 2018
First decision: June 6, 2018
Revised: July 6, 2018
Accepted: August 1, 2018
Article in press: August 1, 2018
Published online: October 16, 2018
Peer-review started: April 30, 2018
First decision: June 6, 2018
Revised: July 6, 2018
Accepted: August 1, 2018
Article in press: August 1, 2018
Published online: October 16, 2018
Core Tip
Core tip: Patients with negative findings in oesophagogastroduodenoscopy and colonoscopy with suspected obscure gastrointestinal-bleeding benefit from further capsule endoscopy (CE) study. Premenopausal women are frequently referred for CE. However in this subset of patients the pretest probability of positive findings is thought to be low. This paper compared the diagnostic yield (DY) as well as therapeutic yield (TY), rebleeding, hospitalization and mortality between premenopausal and menopausal women. We found that menopause status was significantly associated with positive findings, DY, TY, rebleeding and lower time to rebleed. This may lead to consider the exclusion of other comorbid pathologies in fertile age women before CE.