Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Dec 16, 2023; 15(12): 699-704
Published online Dec 16, 2023. doi: 10.4253/wjge.v15.i12.699
Evaluation of appendiceal mucinous neoplasms by curved linear-array echoendoscope: A preliminary study
Jing-Chao Zhang, Yang-Yang Ma, Yong-Zhen Lan, Shuang-Biao Li, Xiao Wang, Jin-Long Hu
Jing-Chao Zhang, Yong-Zhen Lan, Xiao Wang, Endoscopy Center, Hebei Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine, Cangzhou 061000, Hebei Province, China
Yang-Yang Ma, Department of Gastrointestinal Surgery, Hebei Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine, Cangzhou 061000, Hebei Province, China
Shuang-Biao Li, Department of Pathology, Hebei Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine, Cangzhou 061000, Hebei Province, China
Jin-Long Hu, Department of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang 110001, Liaoning Province, China
Author contributions: Hu JL, Zhang JC, Ma YY, and Lan YZ designed and performed the research study; Hu JL, Li SB, and Wang X analyzed the data and wrote the manuscript; and all authors have read and approve the final manuscript.
Supported by Hebei Medical Science Research Project, No. 20191279.
Institutional review board statement: This study was approved by the institutional review board of Hebei Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine.
Informed consent statement: The study was a retrospective study and patients were not required to give informed consent to the study because the identified patient data was used from hospital database.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at hujl@sj-hospital.org.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jin-Long Hu, PhD, Doctor, Department of Gastroenterology, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Shenyang 110001, Liaoning Province, China. 360484590@qq.com
Received: November 10, 2023
Peer-review started: November 10, 2023
First decision: November 21, 2023
Revised: November 25, 2023
Accepted: December 6, 2023
Article in press: December 6, 2023
Published online: December 16, 2023
ARTICLE HIGHLIGHTS
Research background

Appendiceal mucinous neoplasms can present in a malignant fashion, but preoperative diagnosis of appendiceal mucinous neoplasms is difficult. Endoscopy plays an important role in the diagnosis of appendiceal mucinous neoplasms. There are limited reports regarding the endosonographic characteristics of these neoplasms.

Research motivation

We evaluated the imaging features of appendiceal mucinous neoplasms using endoscopic ultrasound (EUS) by curved linear-array echoendoscope.

Research objectives

To describe image features on endoscopic and echoendosonograhic views of appendiceal mucinous neoplasms.

Research methods

The EUS characteristics and patients’ clinical data were reviewed.

Research results

The appendiceal orifice located on the surface of the lesion in 2 cases (volcano sign) and the appendiceal orifice located on the surface of the lesion with white secretion in 2 cases (atypical volcano sign) were seen. EUS showed that the lesions were submucosal cystic hypoechoic lesions with clear boundaries and no wall nodules were observed. Onion-peeling sign, which was defined as intermittent hyperechoic lines in the hypoechoic lesion, could be observed in part of cases.

Research conclusions

This study demonstrated that we can safely evaluate the lesion in the ileocecal region by using a linear-array echoendoscope. A volcano sign on endoscopic view and EUS features could be used to diagnose appendiceal mucinous neoplasms.

Research perspectives

In the future, for difficult colonoscopy, the safety of intubation of linear echoendoscope into cecum should be studied.