Impact of sarcopenia on mortality in patients undergoing liver re-transplantation

Table 1 Demographics and biochemical variables in our patient population

Potential confounder	n	Sarcopenia [Median (IQR) or n (%)]	No sarcopenia [Median (IQR) or n (%)]	P value
Age (yr)	55	49.5 (34, 59)	50 (34, 59)	0.906
Male sex	55	7 (27)	25 (86)	< 0.001
BMI	55	24 (23, 29)	24.7 (21.7, 30.9)	0.781
MELD1	55	28 (24, 33)	28 (24, 33)	0.846
Time between 1st and 2nd OLT (mo)	55	16.7 (5.2, 108.1)	36.5 (7.4, 121.4)	0.337
Albumin	55	2.6 (2.1, 3.3)	2.7 (2.4, 3.1)	0.685
Platelets	55	100 (75, 189)	127 (79, 189)	0.544
Cr	55	1.24 (0.87, 1.76)	1.55 (1.26, 2.01)	0.149
INR	55	1.3 (1.1, 2.1)	1.5 (1.1, 1.8)	0.892
Na	55	136 (132, 139)	136 (134, 138)	0.716
Ascites	55	21 (81)	18 (62)	0.127

IQR: Interquartile range; BMI: Body mass index; Cr: Creatinine; MELD: Model for end-stage liver disease; OLT: Orthotopic liver transplantation; INR: International normalized ratio; Na: Sodium.

Table 2 Associations between sarcopenia status and outcomes

Outcome	n	Sarcopenia Median (IQR) or n (%)]	No Sarcopenia Median (IQR) or n (%)]	P value
Post-op survival for 90 d	55	23 (88)	26 (90)	1.000
Post-op survival for 1 yr	52	19 (76)	22 (81)	0.740
Post-op survival for 5 yr	41	13 (59)	13 (68)	0.746
ICU length of stay (d)	55	3 (2, 4)	2 (2, 5)	0.696
Readmission to ICU	54	4 (15)	4 (14)	1.000
Total length of stay (d)	55	13.5 (10, 27)	21 (9, 28)	0.661
Intubation days	55	1.5 (1, 3)	1 (1, 3)	0.484
Pulmonary complications	54	10 (38)	5 (18)	0.131
Need for dialysis	54	6 (23)	7 (25)	1.000
Readmission within 30 d	55	13 (50)	13 (45)	0.790
PNF	55	2 (8)	0 (0)	0.219
Acute rejection	55	2 (8)	4 (14)	0.672
Arterial complications	55	6 (23)	5 (17)	0.739
Biliary complications	55	8 (31)	10 (34)	1.000

IQR: Interquartile range; ICU: Intensive care unit; PNF: Primary non-function.