Occult hepatitis B virus infection and surgical outcomes in non-B, non-C patients with curative resection for hepatocellular carcinoma

Table 4 Uni- and multi-variate analyses for overall survival after hepatic resection

Characteristic	n	Univariate analysis		Multivariate analysis
		HR (95%CI)	P-value	HR (95%CI)	P-value
Age			0.8321		0.6843
≤ 69	39	1		1
> 69	39	0.94 (0.50-1.73)		0.87 (0.45-1.67)
Gender			0.2713		0.342
Female	17	1		1
Male	61	1.54 (0.73-3.80)		1.51 (0.68-3.85)
Occult HBV infection			0.6039		0.5263
Absent	51	1		1
Present	27	1.18 (0.61-2.20)		1.23 (0.63-2.31)
Alcohol abuse			0.3061
Absent	59	1
Present	19	1.45 (0.69-2.82)
Diabetes mellitus			0.2441
Absent	51	1
Present	27	1.45 (0.76-2.67)
NASH			0.7366
Absent	70	1
Present	8	0.84 (0.25-2.10)
Obesity			0.9432
Absent	54	1
Present	24	1.02 (0.51-1.93)
Fibrosis			0.7084
F0-2	44	1
F3,4	34	1.12 (0.60-2.06)
Vp			0.022		0.0378
Absent	47	1		1
Present	31	2.06 (1.11-3.81)		2.34 (1.05-5.24)
T12/T34			0.0767		0.3344
T12	38	1		1
T34	40	1.73 (0.94-3.27)		0.58 (0.20-1.73)
Solitary/multiple			0.0334		0.0809
Solitary	47	1		1
Multiple	31	1.94 (1.05-3.58)		2.17 (0.92-5.25)

HR: Hazard ratio; CI: Confidence interval; Vp: Portal vein invasion; NASH: Non-alcoholic steatohepatitis; HBV: Hepatitis B virus.