Cockcroft-Gault revisited: New de-liver-ance on recommendations for use in cirrhosis

Table 3 Results from Dooley et al[21] illustrated that rounding of serum creatinine to 0.6 mg/dL underestimated creatinine clearance by 7%; of note, the majority of clinicians round low serum creatinine values to 0.8 or 1.0 mg/dL

		Mean ± SD (mL/min)	Range (mL/min)	Mean % error	P value
DTPA	All	111 ± 46	45-256
	≤ 100 mL/min	77 ± 14	45-96
	> 100 mL/min	140 ± 45	103-256
CG (no rounding)	All	117 ± 38	55-207	12.9	0.352
	≤ 100 mL/min	98 ± 28	55-152	29.2	0.024
	> 100 mL/min	135 ± 38	86-207	-0.1	0.631
CG (rounding SCr to 0.6 mg/dL)	All	97 ± 30	46-172	-7.0	0.029
	≤ 100 mL/min	82 ± 23	46-127	7.9	0.543
	> 100 mL/min	110 ± 29	72-172	-18.9	0.003

CG: Cockcroft-Gault; DTPA: Diethyl triamine penta-acetic acid; SCr: Serum creatinine.