Impact of transjugular intrahepatic porto-systemic shunt on post liver transplantation outcomes: Study based on the United Network for Organ Sharing database

Table 1 Demographics and clinical variables categorized by transjugular intrahepatic porto-systemic shunt status

Variables	TIPS on waitlist (n = 1366; % or mean ± SD)	Non TIPS on waitlist (n = 31417; % or mean ± SD)	P-values
Male candidate	943 (69)	21374 (68)	0.43
Candidate race			< 0.001
White	1072 (78.4)	23063 (73.4)
Black	75 (5.4)	2865 (9.1)
Other	219 (16)	5489 (17.4)
Diabetes mellitus	380 (28)	7769 (24.8)	0.009
ALD	311 (22.7)	6615 (21)	0.13
Hepatic encephalopathy			0.01
None	373 (27.3)	8409 (26.7)
Grade 1-2	925 (67.7)	20790 (66.1)
Grade 3-4	68 (4.9)	2218 (7)
Arterial hypertension	68 (14.8)	2254 (19.7)	0.01
Age	53.5 ± 8.5	53.6 ± 9.3	0.65
MELD score at listing	16.6 ± 6.6	19.66 ± 8.8	< 0.001
Creatinine	1.2 ± 0.8	1.4 ± 1.2	< 0.001
Bilirubin	4.1 ± 6.3	6.61 ± 9.0	< 0.001
INR	1.5 ± 0.4	1.7 ± 0.8	< 0.001
Albumin	2.9 ± 0.6	2.9 ± 0.6	0.66
BMI at list entry
Continuous (kg/m2)	28.8 ± 5.6	28.8 ± 5.7	0.89
Dichotomous (≥ 26 kg/m2)	905 (66.4)	20747 (66.2)	0.85
Cold ischemia time
Continuous (h)	7.1 ± 3.7	6.9 ± 3.5	0.03
Dichotomous (> 12 h)	66 (5.0)	1360 (4.5)	0.38
MELD score at transplantation	23.1 ± 9.1	22.6 ± 9.7	0.03

TIPS: Transjugular intrahepatic porto-systemic shunt; ALD: Alcoholic liver disease; MELD: Model for end-stage liver disease; INR: International normalized ratio; BMI: Body mass index.