Risk factors for acute kidney injury after partial hepatectomy

Table 2 Preoperative patient characteristics according to the occurrence of postoperative acute kidney injury in 466 partial hepatectomies n (%)

	No AKI (n = 366)	AKI (n = 80)	P
Gender, male	180 (49.2)	43 (53.8)	0.269
Age (years), mean (SD)	54.6 (16.57)	57.4 (16.10)	0.842
ACE inhibitors	19 (5.2)	10 (12.5)	0.210
NSAIDs	26 (7.1)	10 (12.5)	0.082
Non-dialytic CKI	1 (0.27)	8 (10.0)	< 0.001
Diabetes mellitus	44 (12.0)	14 (17.5)	0.121
Systemic arterial hypertension	70 (19.1)	15 (18.8)	0.467
Preoperative chemotherapy	85 (23.2)	24 (30.0)	0.402
Cirrhosis	23 (6.3)	10 (12.5)	0.042
MELD score, mean (SD)	7.67 (1.15)	8.05 (1.05)	0.020
Biliary obstruction	6 (1.6)	13 (16.2)	< 0.001
Baseline laboratory tests
Serum urea (mg/dL), mean ± SD	31.45 ± 10.71	35.63 ± 23.77	0.021
Serum creatinine (mg/dL), mean ± SD	0.90 ± 0.71	0.98 ± 0.62	0.229
eGFR (mL/min per square meter), mean ± SD	98.38 ± 51.32	89.86 ± 35.46	0.944
Sodium (mEq/L), mean ± SD	135.67 ± 3.25	134.25 ± 3.00	0.350
Potassium (mEq/L), mean ± SD	4.44 ± 0.63	4.34 ± 0.75	0.697
INR, mean ± SD	1.13 ± 0.45	1.14 ± 0.20	0.912
Bilirrubin (mg/dL), mean ± SD	1.63 ± 3.05	2.84 ± 3.95	0.002
Albumin (g/dL), mean ± SD	3.61 ± 0.87	3.41 ± 0.92	0.505
Platelets (mm3), mean ± SD	211869.55 ± 103744.67	215522.81 ± 115186.57	0.129

AKI: Acute kidney injury; ACE: Angiotensin conversion enzyme; NSAIDs: Non-steroidal anti-inflamatory drugs; CKI: Chronic kidney injury; MELD: Model for End-Stage Liver Disease; INR: International normalized ratio.