Prevalence and risk factors of acute-on-chronic liver failure in a single center from Argentina

Table 1 Chronic liver failure-sequential organ failure assessment score

Organ/system	0	1	2	3	4
Liver (bilirubin, mg/dL)	< 1.2	≥ 1.2 to ≤ 2	≥ 2 to < 6	≥ 6 to < 12	≥ 12
Kidney (creatinine, mg/dL)	< 1.2	≥ 1.2 to < 2	≥ 2 to < 3.5	≥ 3.5 to < 5 or dialysis	≥ 5 or diálysis
Cerebral (HE grade)	No HE	I	II	III	IV
Coagulation (RIN, platelet count)	< 1.1	≥ 1.1 to < 1.25	≥ 1.25 to < 1.5	≥ 1.5 to < 2.5	≥ 2.5 or platelet count ≤ 20000 per cubic millimeter
Circulation (mean arterial pressure, mmHg), inotropic drugs (μg/kg per minute)	≥ 70	< 70	Dopamine ≤ 5 or dobutamine or terlipressin	Dopamine > 5 or E ≤ 0.1 or NE ≤ 0.1	Dopamine > 15 or E > 0.1 or NE > 0.1
Lungs (SpO2/FiO2)	> 512	> 357 a ≤ 512	> 214 a ≤ 357	> 89 to ≤ 214	≤ 89

The text in bold indicates the diagnostic criteria for organ failure. HE: Hepatic encephalopathy; E: Epinephrine; NE: Norepinephrine; FiO₂: Fraction of inspired oxygen; SpO₂: Pulse oximetric saturation.