Resection margin influences the outcome of patients with bilobar colorectal liver metastases

Table 2 Statistical analysis of prognostic factors with respect to disease-free survival

Demographic, clinical and pathological factors	Survival [median (range) mo]	Uni-variate analysis
Demographic factors
Age		0.099
< 65 yr (n = 43)	6 (3-36)
≥ 65 yr (n = 28)	12 (2-36)
Gender		0.343
Male (n = 50)	6 (3-36)
Female (n = 21)	5 (2-36)
Presentation		0.755
Synchronous (n = 35)	6 (2-36)
Metachronous (n = 36)	6 (3-36)
Surgical factors
Less than hemi-hepatectomy (n = 49)	6 (2-36)	0.760
Hemi-hepatectomy or more (n = 22)	6 (2-36)
Histo-pathological factor
Largest tumour size		0.813
< 5 cm (n = 60)	6 (2-36)
≥ 5 cm (n = 11)	9 (2-36)
No. of metastases		0.538
< 4 (n = 44)	7 (2-36)
> 5 (n = 27)	6 (3-36)
Lymphatic invasion		0.256
Positive (n = 15)	6 (2-24)
Negative (n = 56)	6 (2-36)
Vascular invasion		0.775
Positive (n = 28)	6 (2-36)
Negative (n = 43)	7 (2-36)
Peri-neural invasion		0.115
Positive (n = 9)	6 (2-24)
Negative (n = 62)	6 (2-36)
Biliary invasion		0.919
Positive (n = 25)	6 (2-36)
Negative (n = 46)	6 (2-36)
Resection margin (R0)		0.017
R0 (n = 40)	8 (2-36)
R1 (n = 31)	6 (2-36)