Safe and effective sofosbuvir-based therapy in patients with mental health disease on hepatitis C virus treatment

Figure 2 Beck’s Depression Inventory scores among participants with hepatitis C/human immunodeficiency virus coinfection and treated with ledipasvir-sofosbuvir and interferon-based therapy. A: Mean BDI scores pre-, during, and post-treatment among all participants; Decrease in mean score from baseline to during treatment, ^aP = 0.0034, DAA vs IFN; Decrease in mean score from baseline to post-treatment, ^bP = 0.0012, DAA vs IFN; B: Change in mean BDI scores from baseline to post-treatment among participants who achieved SVR, ^dP = 0.0004, DAA vs IFN. SVR: Sustained virologic response; BDI: Beck’s Depression Inventory; DAA: Directly acting antiviral; IFN: Interferon.