Potential role of killer immunoglobulin receptor genes among individuals vaccinated against hepatitis B virus in Lebanon

Table 4 Killer immunoglobulin receptor gene frequencies among study participants vaccinated against hepatitis B virus as compared to non-vaccinated subjects n (%)

KIR genes	Vaccinated (n = 74)	Non-vaccinated (n = 25)	Test1	OR (95%CI)	P value
2DL2	41 (55.40)	15 (60.00)	0.161	0.83 (0.33-2.082)	0.436
2DL3	63 (85.10)	20 (80.00)	0.364	1.43 (0.44-4.62)	0.374
2DL5A	21 (28.40)	4 (16.00)	1.517	2.08 (0.64-6.79)	0.168
2DL5B	24 (32.40)	5 (20.00)	1.395	1.92 (0.64-5.73)	0.178
2DS1	30 (40.50)	10 (40.00)	0.002	1.02 (0.41-2.58)	0.577
2DS2	40 (54.10)	15 (60.00)	0.268	0.78 (0.31-1.97)	0.39
2DS3	32 (43.20)	14 (56.00)	1.223	0.60 (0.24-1.49)	0.191
2DS4*001/002	28 (37.80)	11 (44.00)	0.297	0.77 (0.31-1.94)	0.376
2DS4*003/007	60 (81.10)	22 (88.00)	FET	0.58 (0.15-2.23)	0.324
2DS5	27 (36.50)	7 (28.00)	0.597	1.47 (0.55-3.99)	0.302
3DS1	32 (43.20)	9 (36.00)	0.246	1.35 (0.53-3.46)	0.401
3DP*001/002/004	15 (20.30)	2 (8.00)	FET	2.92 (1.62-13.80)	0.134

We compared the frequencies of KIR genes with enough variability between study participants that were vaccinated against hepatitis B virus and those that were not.

¹The statistical test performed to compare the frequencies of KIR gene expression among vaccinated and non-vaccinated study participants whereby FET refers to Fisher’s exact test and the rest of the values represent the Pearson χ² value. KIR: Killer immunoglobulin receptor; FET: Fisher-exact test; OR: Odds ratio.