Independent effects of diet and exercise training on fat oxidation in non-alcoholic fatty liver disease

Table 4 Maximal aerobic power and substrate oxidation during exercise pre-intervention, and after 6 mo of energy restriction or exercise treatment (post-intervention)

	Energy restriction (n = 6)			Exercise (n = 10)
	Pre	Post	P	Pre	Post	P
VO2peak (mL/kg per minute)	20.4 ± 5.1	20.7 ± 6.4	0.73	23.9 ± 6.4	28.3 ± 6.3	< 0.001
VO2peak (mL/kgFFM per minute)	32.5 ± 5.0	31.0 ± 5.4	0.31	39.2 ± 8.4	43.6 ± 7.4	0.004
Workload at VO2peak (W)	121 ± 53	121 ± 57	0.94	176 ± 78	224 ± 81	< 0.001
MFO (g/min)	0.14 ± 0.13	0.06 ± 0.04	0.17	0.17 ± 0.09	0.29 ± 0.14	0.03
MFO (mg/kgFFM per minute)	2.5 ± 1.7	1.2 ± 0.7	0.18	2.8 ± 1.5	4.4 ± 1.9	0.04
Workload at MFO (W)	44.8 ± 16.5	41.3 ± 13.4	0.43	44.7 ± 19.5	76.3 ± 46.0	0.03
Fatmax (%VO2peak)	48.7 ± 14.7	47.9 ± 8.8	0.62	45.2 ± 12.3	47.0 ± 7.2	0.94

Complete-case analysis performed. VO_2peak: Peak oxygen uptake; MFO: Maximal fat oxidation; W: Watts; Fat_max: Exercise intensity eliciting maximal fat oxidation; FFM: Fat-free mass.