Metastatic recurrence to a solitary lymph node four years after hepatic lobectomy for primary hepatocellular carcinoma

Figure 3 Resected recurrence. A: The H and E-stained shows a tiny area of likely LN at one end; B: Shows obvious tumor cells nests; On the right-hand set of IHC stained split full-height images, both the main mass (F-H); and obvious nodal tumor (LN2) (C-E), are strongly positive on G3 (C), CK19 (D), and HP1 (E) stains. Mass: Main mass; LN: Lymph node; G3: Glypican 3; CK19: Cytokeratin 19; HP1: Hepatocyte paraffin 1.