Contribution of alpha-fetoprotein in liver transplantation for hepatocellular carcinoma

Table 3 Suggestions for new selection criteria for liver transplantation that integrate α-fetoprotein

Ref.	Year	No. of patients	Study design	Criteria	AFP cut-off values
Yang et al[56]	2007	63	Retrospective	AFP	20 ng/mL, 200 ng/mL, 1000 ng/mL
				Tumor size
				Number of tumors
Zheng et al[63]	2008	195	Retrospective	AFP	400 ng/mL
				Total tumor diameter
				Histopathologic grade
Lai et al[64]	2012	158	Retrospective	AFP	400 ng/mL
				Total tumor diameter
Duvoux et al[57]	2012	435	Prospective	AFP	100 ng/mL, 1000 ng/mL
				Tumor size
				Number of tumors
Kashkoush et al[76]	2014	115	Retrospective	AFP	400 ng/mL
				Actual tumor volume
Toso et al[75]	2015	233	Prospective	AFP	400 ng/mL
				Total tumor volume
Hong et al[77]	2015	123	Retrospective	AFP	200 ng/mL
				F-FDG PET positivity

AFP: Alpha-fetoprotein; F-FDG PET: F-fluorodeoxyglucose positron emission tomography.