Usefulness of staging systems and prognostic scores for hepatocellular carcinoma treatments

Table 4 Barcelona Clinic Liver Cancer C hepatocellular carcinoma, a broad spectrum of tumors; example of the Advanced Liver Cancer Prognostic System score[36]

Parameters	Points
Ascites	2
Abdominal pain	2
Weight loss	2
Child-Pugh grade A/B/C	0/2/5
alkaline phosphatase, UI/L > 200	3
Bilirubin, mcmol/L ≤ 33/> 33- ≤ 50/> 50	0/1/3
Urea, mmol/L > 8.9	2
Portal vein thrombosis	3
Tumor size: Diffuse/> 5 cm/ ≤ 5 cm	4/3/0
Lung metastases	3
AFP, ng/mL > 400	4
Probability of patients surviving at least 3 mo estimated by the ALCPS score[36]
Score ≤ 8 points: 82.0% (95%CI: 76.5%-87.5%)
Score 9-15 points: 53.4% (95%CI: 48.3%-57.7%)
Score ≥ 16 points: 18.9% (95%CI: 14.7%-23.3%)

Probability of patients surviving at least 3 mo estimated by the ALCPS score[36]. AFP: Alpha-fetoprotein; ALCPS: Advanced Liver Cancer Prognostic System.