Incidence, risk factors and outcome of de novo tumors in liver transplant recipients focusing on alcoholic cirrhosis

Table 2 Comparative studies between alcoholic cirrhotic and non-alcoholic cirrhotic patients who underwent orthotopic liver transplantation, incidence of de novo tumors n (%)

Ref.	No. OLT	Follow-up period	DNT overall incidence	DNT-AC	DNT-non-AC	P-value	DNT excluded
Duvoux et al[9]	90	45.2 ± 21.2 mo	11 (12.2)	8 (26.7)	3 (5)	0.01	-
Jain et al[23]	834	9 4 ± 11 mo	81 (9.7)	36 (19.4)	45 (6.9)	< 0.05 (UAD)	-
Bellamy et al[24]	513	81.7 mo	57 (11.3)	33 (26)	24 (6.1)	0.0001	PTLD
Saigal et al[26]	1140	69 mo	30 (2.6)	10 (7.5)	20 (1)	0.001	-
Benlloch et al[11]	772	40 mo	41 (5.3)	18 (9.4)	23 (3.9)	0.01	Skin DNT
Oo et al[12]	1778	-	141 (7.9)	15 (8.8)	126 (7.8)	0.001	-
Dumortier et al[13]	594	-	42 (7)	37 (12.1)	5 (1.7)	0.05	-
Jiménez et al[28]	701	9-206 mo	109 (15.5)	69 (25)	40 (9.4)	0.001	-
Biselli et al[29]	147	-	11 (7.5)	7 (14.3)	4 (4)	0.042	-
Zanus et al[15]	638	48 mo	43 (6.3)	16 (11)	27 (5)	0.02	-

AC: Alcoholic cirrhosis; OLT: Orthotopic liver transplantation; PTLD: Post-transplant lymphoproliferative disease; DNT: De novo tumors; UAD: Upper aerodigestive tumor.