Aetiological factors of Budd-Chiari syndrome in Algeria

Table 4 Budd-Chiari syndrome aetiologies

Aetiologies	Tested patients	n	% (n/tested n)
MPD	104	36	34.6
Patent		19
Latent		17
APL syndrome	92	20	21.7
Protein C deficiency	67	13	19.4
Protein S deficiency	59	5	8.5
Antithrombin deficiency	68	0	0
APCR	68	7	10.3
Celiac disease	88	10	11.4
Hyperhomocysteinaemia	42	5	11.9
PNH	11	4
Systemic disease1	106	6	5.6
Inflammatory bowel disease2	60	5	8.3
Gene II mutation	21	1	4.7
Liver hydatic cyst	115	5	4.3
Hepatocellular carcinoma	115	1	0.8
Hormonal factors	70	25	35.7
Oral contraception	70	24	34.3
Pregnancy	70	3	4.3
Hormonal treatment	70	1	1.4
Unknown aetiology		24	20.9

¹Systemic lupus erythematosus (n = 1), granulomatosis (n = 1), sarcoidosis (n = 1), Behçet disease (n = 3);

²Ulcerative colitis (n = 1), Crohn’s disease (n = 4). PNH: Paroxysmal nocturnal haemoglobinuria; APL: Anti-phospholipid syndrome; APCR: Activated protein C resistance; MPD: Myeloproliferative disease.