Staging systems for hepatocellular carcinoma: Current status and future perspectives

Table 5 American Joint Committee on Cancer /TNM 7^th edition

Primary tumor	Description
T1	Single tumor without vascular invasion
T2	Single tumor with vascular invasion or multiple tumors, none > 5 cm
T3a	Multiple tumors, any > 5 cm
T3b	Single tumor or multiple tumors of any size involving a major branch of the portal vein or hepatic vein
T4	Tumors with direct invasion of adjacent organs or perforation of visceral peritoneum
Stage grouping
StageI	T1	N0	M0
Stage II	T2	N0	M0
Stage III A	T3a	N0	M0
Stage III B	T3b	N0	M0
Stage III C	T4	N0	M0
Stage IV A	Any T	N1	M0
Stage IV B	Any T	Any N	M1