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©The Author(s) 2015.
World J Hepatol. Dec 18, 2015; 7(29): 2896-2905
Published online Dec 18, 2015. doi: 10.4254/wjh.v7.i29.2896
Table 2 Diagnostic criteria for recurrent primary biliary cirrhosis after liver transplantation[49]
Confirmed diagnosis of PBC in the explant histology
Characteristic histologic features1
Lymphoplasmacytic portal infiltrate
Lymphoid aggregates
Epithelioid granulomas
Evidence of bile duct injury
Persistence of AMA or AMA-M2
Exclusion of other causes of graft dysfunction
Acute and chronic rejection
Graft vs host disease
Bile flow impairment or cholangitis
Vascular complications
Viral hepatitis
Drug induced hepatitis


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