Review
Copyright ©The Author(s) 2015.
World J Hepatol. Nov 18, 2015; 7(26): 2664-2675
Published online Nov 18, 2015. doi: 10.4254/wjh.v7.i26.2664
Table 2 Urinary markers of hepatocellular carcinoma
YearUrinary biomarker
Nucleosides and nucleotides
1974Methylated purines[45]
1976Cyclic GMP[46,47]
1986Pseudouridine[48,49]
Proteins and polyamines
1990TGFα and β[50-52]
1998Neopterin[53-56]
2004Urinary trypsin inhibitor[59,60]
1998Spermine, putrescine, spermidine[58]
Metabolite profiles
2009Octanedioic acid, glycine and hypoxanthine[61]
2010Creatinine, carnitine, creatine[62]