Current biomarkers for hepatocellular carcinoma: Surveillance, diagnosis and prediction of prognosis

Table 3 Genetic signatures from tumor tissue and their prognostic significance

Ref.	Year	Correlation with	No. of genes in signature	AUC	P-value
Nault et al[95]	2013	Disease-free survival after resection	5 (tumor)	0.8	< 0.0001
Lim et al[96]	2013	Disease-free survival after resection	25 (tumor)		0.002
Kurokawa et al[97]	2004	Tumor recurrence after resection	20 (tumor)		0.001
Yoshioka et al[98]	2009	Tumor recurrence after resection	172 (tumor)		< 0.0001
Woo et al[99]	2008	Recurrence free survival	628 (tumor)		< 0.01

AUC: Area under the cure.