Retrospective Study
Copyright ©The Author(s) 2015.
World J Hepatol. Jun 28, 2015; 7(12): 1685-1693
Published online Jun 28, 2015. doi: 10.4254/wjh.v7.i12.1685
Table 1 Baseline characteristics of the patients treated with tolvaptan and controls
CharacteristicTLV group (n = 60)Controls (n = 60)P
Age (yr)67.1 ± 11.269.5 ± 9.00.21
Male46 (76.7%)46 (76.7%)1.00
Bodyweight (kg)61 (54-69)64 (55-73)0.58
HCV antibody positive36 (60.0%)35 (58.3%)1.00
Child-Pugh class C27 (45.0%)24 (40.0%)0.71
Refractory ascites56 (93.3%)60 (100%)0.12
Hepatic hydrothorax32 (53.3%)29 (48.3%)0.72
Liver neoplasms stage 3, 4a, or 4b26 (43.3%)25 (41.7%)1.00
Serum albumin (g/dL)2.8 (2.5-3.1)2.8 (2.5-3.1)0.98
Total bilirubin (mg/dL)2.7 (0.7-3.1)2.8 (1.1-3.6)0.81
ALT (IU/L)42 (20-44)36 (20-53)0.27
Serum creatinine (mg/dL)1.40 (0.90-1.61)1.45 (0.78-1.59)0.30
eGFR (mL/min per 1.73 m2)43.1 (31.0-62.7)49.8 (33.5-67.8)0.95
Serum sodium (mEq/L)133 (130-136)136 (132-139)0.02
Platelet count (× 103/μL)114 (58-147)95 (69-139)0.80
Prothrombin activity (%)58.7 (45.0-70.0)57.3 (42.3-70.2)0.71