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Copyright ©2014 Baishideng Publishing Group Inc.
World J Hepatol. May 27, 2014; 6(5): 326-339
Published online May 27, 2014. doi: 10.4254/wjh.v6.i5.326
Table 8 Adverse event structure for asunaprevir
Lok et al[35] AI447-011
Suzuki et al[36]
ASV + DCV + conventional therapy(n = 10)ASV + DCV(n = 11)Null response (n = 21)Contraindications to IFN-based therapy (n = 22)
Diarrhea70.0%72.7%43%9%
Fatigue70.0%54.5%-1-1
Headache50.0%45.5%38%27%
Nausea50.0%18.2%-1-1
Coughing20.0%27.3%-1-1
Subfebrile temperature27.3%10.0%14%23%