Transitions of histopathologic criteria for diagnosis of nonalcoholic fatty liver disease during the last three decades

Figure 2 Typical immnohistochemical findings of nonalcoholic steatohepatitis. A: Cytokeratin (CK)18; B: Ubiquitin. Stained (brown) small aggregates are seen in ballooned hepatocytes with CK18-negative cytoplasms (arrows) [Immunoperoxidase; original magnifications, (A) × 150 and (B) × 200].