Review
Copyright ©2014 Baishideng Publishing Group Inc.
World J Hepatol. Oct 27, 2014; 6(10): 704-715
Published online Oct 27, 2014. doi: 10.4254/wjh.v6.i10.704
Table 1 Studies reporting the outcome of Laser Ablation for small hepatocellular carcinoma
Ref.Pts/Tumors noTumor size (cm) meanComplete ablationa, %Local recurrence rate, %Overall survival %
3-yr disease-free survival %Major complication rateb, %Mortality rate, %P value
3-yr5-yr
Giorgio et al[31] (2000)77/85 ≤ 4.0c82f1.13.9d1.3d
Pacella et al[73] (2001)30/30> 5.090f (+ TACE)74000
30/15 ≤ 3.0100f000
Child-Pugh A600.001
Child-Pugh B0
Pacella et al[66] (2001)74/92 ≤ 4.0c97f6681500
Child-Pugh A73310.052
Child-Pugh B7,8,9680
Eichler et al[61] (2001)39/61 ≤ 5.0e97.5g04.4 yr00
Pacella et al[42] (2005)82/99 ≤ 4.0c90.9f8.81.50
Francica et al[64] (2007)148/169 ≤ 4.0c82f14.752270.60.6
≤ 2.095f5
≤ 3.089f15
> 3.074f260.001
Well-differentiated ≤ 3.0058
Poorly-differentiated250.008
Pacella et al[68] (2009)1432/548 ≤ 4.0c79.6f20261341.60.2
≤ 2.085.1f41
Child-Pugh A63
Child-Pugh A ≤ 2.0683
Francica et al[53] (2012)106/1164 ≤ 4.0c92.2f10.60.90.5NS
58/66 ≤ 4.0c95.5f
Francica et al[65] (2012)116/132 ≤ 4.0c100f18.057290.0295
2.25
Eichler et al[44] (2012)113/175 ≤ 5.0e98g1.1543000
Di Costanzo et al[43] (2013)104/116 ≤ 6.087.6f16
≤ 5.091.7f
Di Costanzo et al[72] (2013)670/80 (LA) ≤ 5.0696.3f23.9664200
70/77 ≤ 5.0697.4f25.75943000.693