Noninvasive assessment of liver damage in chronic hepatitis B

Table 1 Comparison of clinical and laboratory parameters between control and hepatitis B patients groups

Variable	Control (n = 43)	Hepatitis B patients (n = 89)	P value
Gender (female/male)	31 (72.1)/12 (27.9)	39 (43.8)/50 (56.2)	0.004
Age (yr)	35.4 ± 12.64	41.5 ±1 3.02	0.012
Platelet count (103μL)	272.0 (242-342)	179.0 (147-231)	< 0.001
Total bilirubin (mg/dL)	0.6 (0.4-0.8)	0.8 (0.6-1)	0.009
AST (IU/L)	17.0 (14-20)	45.0 (30-68)	< 0.001
ALT (IU/L)	16.0 (11-19)	56.0 (36-111)	< 0.001
AP (IU/L)	69.0 (53-79)	72.0 (61-90)	0.086
GGT (IU/L)	17.0 (14-27)	29.0 (21-50)	< 0.001
Neutrophil count	4.3 (3.4-4.9)	3.4 (2.9-4.7)	0.004
Lymphocyte count	2.1 (1.6-2.4)	2.0 (1.6-2.4)	0.355
N/L	2.1 (1.5-2.8)	1.9 (1.4-2.3)	0.123
APRI score	0.1 (0.1-0.1)	0.6 (0.3-1.1)	< 0.001

Values are expressed as n (%), mean ± SD or median (25^th-75^th percentiles). AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; AP: Alkaline phosphatase; GGT: Gamma glutamyl transferase; N/L: Neutrophil-lymphocyte ratio; APRI: Aspartate aminotransferase/platelet ratio index.