Melatonin attenuates high fat diet-induced fatty liver disease in rats

Table 2 Effect of melatonin after adjusting for high fat diet and duration of its use

Melatonin	5 mg/kg	P value	10 mg/kg	P value
Liver weight (g)	-3.9	< 0.001	-3.9	< 0.001
Liver weight/body weight ratio (%)	-0.7	< 0.001	-0.7	< 0.001
Portal vein pressure (mmHg)	-1.6	0.09	-1.4	0.14

Results are expressed as the mean difference between rats on melatonin by comparison to those not on melatonin.