Significance of serum leptin and adiponectin levels in Egyptian patients with chronic hepatitis C virus associated hepatic steatosis and fibrosis

Table 2 Correlation between serum leptin and other parameters in patients studied

Parameter	Group I (n = 30)		Group II (n = 15)
	r	P value	r	P value
Age (yr)	-0.24	> 0.05 NS	-0.77	< 0.0011
BMI (kg/m2)	0.43	< 0.051	0.94	< 0.0011
AST (U/L)	-0.78	< 0.0011	-0.99	< 0.0011
ALT (U/L)	-0.39	< 0.051	-0.51	> 0.05 NS
PT (%)	0.11	> 0.05 NS	0.93	< 0.0011
Protein (gm/dL)	-0.28	> 0.05 NS	-0.39	> 0.05 NS
Albumin (gm/dL)	-0.37	< 0.051	-0.80	< 0.0011
Total bilirubin (mg/dL)	0.64	< 0.0011	0.98	< 0.0011
ALP (U/L)	-0.70	< 0.0011	-0.95	< 0.0011
Urea (mg/dL)	-0.25	> 0.05 NS	0.95	< 0.0011
Creatinine (mg/dL)	-0.38	< 0.051	0.97	< 0.0011
Adiponectin (pg/mL)	0.09	> 0.05 NS	-0.10	> 0.05 NS

¹Significant. Group I: Patients with hepatic steatosis; Group II: Patients with hepatic fibrosis. NS: Non significant; BMI: Body mass index; AST: Aspartate transaminase; ALT: Alanine aminotransferase; PT: Prothrombin activity; ALP: Alkaline phosphatase.