Evaluation of adherence to oral antiviral hepatitis B treatment using structured questionnaires

Table 3 Treatment and disease related characteristics of the study participants and association with adherence to nucleos(t)ide analogues (n = 80) n (%)

Characteristics	Patients	Optimal adherence	P value
Patients			0.24
Treatment duration > 1 yr	16 (21.1)	8 (53.3)
Treatment duration < 1 yr	60 (78.9)	39 (69.9)
Adherence to other prescription pills			0.04
Suboptimal	11 (45.8)	4 (40.0)
Optimal	13 (54.2)	13 (100.0)
Follow dose scheduling instructions			0.44
Yes	14 (19.4)	7 (53.8)
No	58 (80.6)	36 (65.5)
Side effect			0.25
Yes	11 (13.8)	6 (54.5)
No	66 (82.5)	42 (68.9)
Don’t know	1 (1.3)	0 (0.00)
Believe in the therapeutic benefit of their antiviral medications			0.29
Yes	64 (80)	40 (67.8)
No	2 (2.5)	2 (100.0)
Don’t know	12 (15.0)	6 (50.0)
Patients’ perception of their health			0.32
Excellent	10 (12.5)	8 (80.0)
Very good	23 (28.8)	11 (52.4)
Good	32 (40)	22 (73.3)
Fair	10 (12.5)	6 (66.7)
Poor	3 (3.8)	1 (33.3)
Patients’ perception of their disease condition			0.64
Severe	2 (2.5)	2 (100.0)
Moderate	15 (8.8)	11 (73.3)
Mild	36 (45.0)	21 (61.8)
Don’t know	25 (31.3)	8 (63.6)
Complications			0.48
Yes	4 (5.1)	2 (50.0)
No	74 (94.9)	47 (67.1)
Cirrhosis- patients’ perception			0.68
Yes	7 (9)	5 (83.3)
No	55 (70.5)	34 (65.4)
Don’t know	16 (20.5)	10 (66.7)
Use of memory aids			0.25
Yes	26 (32.5)	15 (57.7)
No	54 (67.5)	34 (70.8)
Patient understands everything the doctor says during the consultation			0.31
Yes	78 (97.5)	47 (65.3)
No	2 (2.5)	2 (100.0)
Difference in language spoken at home and at consultation with doctor			0.04
Same	42 (52.5)	30 (76.9)
Different	38 (47.5)	19 (54.3)