HBV vaccine efficacy and detection and genotyping of vaccineé asymptomatic breakthrough HBV infection in Egypt

Table 3 Frequency of HBV-DNA by nested Multiplex PCR, HBc and HBe anti bodies among r-HBsAg vaccine responders and non responders

Age group	anti-HBs IgG level	Number of serum samplesTested	HBV-DNA by nestedMultiplex PCR n (%)	HBc antibodyIgG n (%)	HBe IgG antibodyn (%)
Group I Children (2-<4 years)	Low	27	0	0	0
	Negative	8	0	0	0
	High	20	0	0	0
Group II Children (4-13 years)	Low	178	4 (2.5)	2 (1.2)	0
	Negative	53	14 (26.4)	1 (1.9)	1 (1.9)
	High	14	0	0	0
Group III Adults (20-47 years)	Low	32	2a (6.25)	1 (3.1)	1 (3.1)
	Negative	21	2a (9.52)	1 (4.8)	1 (4.8)
	High	7	0	0	0
Total		360	22 (6.11)	5 (1.38)	3 (0.83)

^aThese four +ve sera are also +ve for HBs antigen &HBcAb detected by ELISA.