Splenic stiffness measurement to predict decompensation in compensated advanced chronic liver disease

Table 5 Sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of splenic stiffness measurement compared to other parameters

Parameters	SSM > 57.5 kPa	LSM > 27 kPa	APRI > 1.6	FIB-4 > 4.01	SIP score
Sensitivity	82.04	78.16	59.22	61	87.5%
Specificity	87.50	62.50	79.17	82	82.5%
Area under the curve	0.848	0.703	0.70	0.76	0.89
Positive predictive value	98.26	94.70	96.06	97	36.8%
Negative predictive value	36.21	25.00	18.45	21.5	98.3%
Diagnostic accuracy	82.61	76.50	61.30	64	83.0

SSM: Splenic stiffness measurement; LSM: Liver stiffness measurement; APRI: Aspartate aminotransferase to platelet ratio index; FIB-4: Fibrosis-4 index; SIP: Splenic stiffness measurement-international normalized ratio-platelet score.