Splenic stiffness measurement to predict decompensation in compensated advanced chronic liver disease

doi:10.4254/wjh.124338

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Hepatol. Sep 27, 2026; 18(9): 124338
Published online Sep 27, 2026. doi: 10.4254/wjh.124338

Table 3 Differences in baseline non-invasive parameters in patients who developed decompensation, mean ± SD

Parameters	No decompensation (n = 212)	Decompensation (n = 19)	P value
LSM (kPa)	22.68 ± 7.02	30.77 ± 11.26	< 0.001
SSM (kPa)	43.99 ± 14.81	69.61 ± 16.27	< 0.001
FIB-4	4.28 ± 2.52	5.97 ± 2.31	0.002
APRI	1.68 ± 1.16	2.24 ± 0.95	0.022
Spleen size (cm)	13.41 ± 1.37	14.59 ± 1.02	< 0.001
Liver size (cm)	12.31 ± 1.14	12.2 ± 1.57	0.676
PV diameter (mm)	12.83 ± 0.82	13.11 ± 0.86	0.123

LSM: Liver stiffness measurement; SSM: Splenic stiffness measurement; FIB-4: Fibrosis-4 index; APRI: Aspartate aminotransferase to platelet ratio index; PV: Portal vein.

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Citation: Malakar S, Bhardwaj A, Rungta S, Dhar J, Kapoor V, Roy A, Giri S, Singh V, Samanta J. Splenic stiffness measurement to predict decompensation in compensated advanced chronic liver disease. World J Hepatol 2026; 18(9): 124338
URL: https://www.wjgnet.com/1948-5182/full/v18/i9/124338.htm
DOI: https://dx.doi.org/10.4254/wjh.124338

Malakar S, Bhardwaj A, Rungta S, Dhar J, Kapoor V, Roy A, Giri S, Singh V, Samanta J. Splenic stiffness measurement to predict decompensation in compensated advanced chronic liver disease. World J Hepatol 2026; 18(9): 124338 [DOI: 10.4254/wjh.124338]

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