Effects of fullerenol C60 on hepatic ischemia-reperfusion injury in desflurane-anesthetized rats

doi:10.4254/wjh.122845

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World Journal of Hepatology

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1948-5182

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Hepatol. Sep 27, 2026; 18(9): 122845
Published online Sep 27, 2026. doi: 10.4254/wjh.122845

Table 2 Rat liver tissue oxidative status parameters, mean ± SEM

	Group C (n = 6)	Group IRI (n = 6)	Group IRI-F (n = 6)	Group IRI-D (n = 6)	Group IRI-F-D (n = 6)	P value¹
MDA (nmol/mg protein)	0.10 ± 0.01	0.25 ± 0.01^a	0.14 ± 0.01^a^,^b	0.21 ± 0.01^a^,^b	0.16 ± 0.01^a^,^b	< 0.0001
CAT (IU/mg protein)	385.75 ± 32.07	170.93 ± 11.78^a	327.82 ± 13.84^b	204.95 ± 19.30^a	282.25 ± 23.59^a^,^b	< 0.0001
GST (IU/mg protein)	1.10 ± 0.07	0.58 ± 0.04^a	0.95 ± 0.04^b	0.78 ± 0.05^a	0.82 ± 0.11^a^,^b	< 0.0001
ARE (IU/mg protein)	1.24 ± 0.07	0.78 ± 0.03^a	1.15 ± 0.05^b	1.01 ± 0.07^a^,^b	1.08 ± 0.06^b	< 0.0001

^aP < 0.05 vs control group.

^bP < 0.05 vs ischemia-reperfusion injury group.

¹Determined by Kruskal-Wallis test.

C: Control; IRI: Ischemia-reperfusion injury; IRI-F: Ischemia-reperfusion injury + fullerenol C60; IRI-D: Ischemia-reperfusion injury + desflurane; IRI-F-D: Ischemia-reperfusion injury + fullerenol C60 + desflurane; MDA: Malondialdehyde; CAT: Catalase; GST: Glutathione-S-transferase; ARE: Arylesterase.

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Citation: Kasapbasi E, Ozdemir C, Yavuz A, Sezen SC, Kurtipek O, Kavutçu M, Arslan M. Effects of fullerenol C60 on hepatic ischemia-reperfusion injury in desflurane-anesthetized rats. World J Hepatol 2026; 18(9): 122845
URL: https://www.wjgnet.com/1948-5182/full/v18/i9/122845.htm
DOI: https://dx.doi.org/10.4254/wjh.122845

Kasapbasi E, Ozdemir C, Yavuz A, Sezen SC, Kurtipek O, Kavutçu M, Arslan M. Effects of fullerenol C60 on hepatic ischemia-reperfusion injury in desflurane-anesthetized rats. World J Hepatol 2026; 18(9): 122845 [DOI: 10.4254/wjh.122845]

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