Small dense low-density lipoprotein in primary biliary cholangitis: Independent association with metabolic syndrome

doi:10.4254/wjh.124436

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World Journal of Hepatology

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1948-5182

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Hepatol. Aug 27, 2026; 18(8): 124436
Published online Aug 27, 2026. doi: 10.4254/wjh.124436

Table 8 Receiver operating characteristic analysis of lipoprotein-related parameters for identification of metabolic syndrome

Variable	AUC (95%CI)	P value	Optimal cut-off	Sensitivity (%)	Specificity (%)	Youden index
sdLDL	0.634 (0.540-0.729)	0.006	0.075	46.6	22.2	0.243
largeLDL	0.400 (0.305-0.495)	0.048	2.290	6.9	97.8	0.047
LDL-C	0.378 (0.283-0.473)	0.013	5.360	6.9	98.9	0.058
sdLDL/LargeLDL ratio	0.650 (0.554-0.745)	0.002	0.034	62.1	70.0	0.321

LDL: Low-density lipoprotein cholesterol; sdLDL: Small dense low-density lipoprotein; AUC: Area under the curve; CI: Confidence interval.

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Citation: Koky T, Drazilova S, Janicko M, Harhovsky M, Hubkova B, Tothova I, Rabajdova M, Marekova M, Jarcuska P. Small dense low-density lipoprotein in primary biliary cholangitis: Independent association with metabolic syndrome. World J Hepatol 2026; 18(8): 124436
URL: https://www.wjgnet.com/1948-5182/full/v18/i8/124436.htm
DOI: https://dx.doi.org/10.4254/wjh.124436

Koky T, Drazilova S, Janicko M, Harhovsky M, Hubkova B, Tothova I, Rabajdova M, Marekova M, Jarcuska P. Small dense low-density lipoprotein in primary biliary cholangitis: Independent association with metabolic syndrome. World J Hepatol 2026; 18(8): 124436 [DOI: 10.4254/wjh.124436]

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