Effect of hepatic venous pressure gradient in different hepatic venous branches on assessing portal hypertension in cirrhotic patients

doi:10.4254/wjh.123580

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Aug 27, 2026; 18(8): 123580
Published online Aug 27, 2026. doi: 10.4254/wjh.123580

Table 1 Baseline characteristics of patients in sub-study 1

	All (n = 73)	HBV (n = 43)	ALD (n = 20)	HBV + ALD (n = 10)
Age (year), mean ± SD	53.58 ± 9.10	55.50 ± 9.00	51.10 ± 9.51	50.60 ± 10.24
Male	61 (83.6)	32 (74.4)	19 (95.0)	10 (100.0)
BMI (kg/m²)	22.84 (3.28)	22.12 (3.14)	23.48 (3.36)	23.57 (3.04)
Decompensation, n (%)	59 (80.8)	37 (86.0)	13 (65.0)	9 (90.0)
Variceal bleeding	54 (74.0)	36 (83.7)	9 (45.0)	9 (90.0)
Ascites needing treatment	11 (15.1)	4 (9.3)	5 (25.0)	2 (20.0)
Hepatic encephalopathy	1 (1.4)	0 (0)	1 (5.0)	0 (0)
CSPH, n (%)	63 (86.3)	35 (81.4)	18 (90.0)	10 (100.0)
Etiology, n (%)
HBV	43 (58.9)	NA	NA	NA
ALD	20 (27.4)	NA	NA	NA
HBV and ALD	10 (13.7)	NA	NA	NA
Child-Pugh class, n (%)
Class A	52 (71.2)	35 (81.4)	11 (55.0)	6 (60.0)
Class B	18 (24.6)	7 (16.3)	7 (35.0)	4 (40.0)
Class C	3 (4.1)	1 (2.3)	2 (10.0)	0 (0)
Laboratory test, median (IQR)
PLT (10⁹/L)	54.00 (11.00)	72.00 (52.50)	87.00 (54.75)	72.00 (33.00)
TBIL (μmol/L)	19.60 (19.25)	15.40 (11.10)	27.90 (27.35)	22.35 (22.90)
Hb (10⁹/L)	101.00 (43.00)	109.00 (46.00)	101.00 (50.00)	76.50 (47.50)
ALT (U/L)	25.00 (20.00)	24.00 (15.00)	29.00 (22.25)	25.00 (13.00)
AST (U/L)	34.00 (24.50)	30.00 (13.50)	62.00 (73.75)	40.00 (20.00)
GGT (U/L)	41.50 (67.50)	35.00 (31.25)	132.00 (194.00)	27.00 (57.00)
Alb (g/L)	34.55 (6.50)	37.20 (9.00)	33.00 (5.70)	33.20 (3.90)
Cr (μmol/L)	68.00 (21.00)	72.00 (23.50)	61.00 (15.25)	65.50 (18.00)
PT (seconds)	15.90 (2.50)	15.85 (2.70)	15.95 (3.10)	16.50 (2.10)
INR	1.27 (0.26)	1.26 (0.27)	1.30 (0.32)	1.34 (0.23)

HBV: Hepatitis B virus; ALD: Alcoholic-related liver disease; BMI: Body mass index; CSPH: Clinically significant portal hypertension; IQR: Interquartile range; PLT: Platelet counts; TBIL: Total bilirubin; Hb: Hemoglobin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: Gamma-glutamyl transpeptidase; Alb: Albumin; Cr: Creatinine; PT: Prothrombin time; INR: International normalized ratio.

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Citation: Huang YF, Wu XQ, Yang YD, Ke BL, Luo JN, Chang BY, Zhou CR, Huang XL, Pan XM, Lai XM, Zhang LJ, Wu C, Wu B. Effect of hepatic venous pressure gradient in different hepatic venous branches on assessing portal hypertension in cirrhotic patients. World J Hepatol 2026; 18(8): 123580
URL: https://www.wjgnet.com/1948-5182/full/v18/i8/123580.htm
DOI: https://dx.doi.org/10.4254/wjh.123580

Huang YF, Wu XQ, Yang YD, Ke BL, Luo JN, Chang BY, Zhou CR, Huang XL, Pan XM, Lai XM, Zhang LJ, Wu C, Wu B. Effect of hepatic venous pressure gradient in different hepatic venous branches on assessing portal hypertension in cirrhotic patients. World J Hepatol 2026; 18(8): 123580 [DOI: 10.4254/wjh.123580]

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