Peribiliary and colonic crypt glands in primary sclerosing cholangitis and inflammatory bowel disease pathogenesis: New research perspectives

doi:10.4254/wjh.123377

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Hepatol. Aug 27, 2026; 18(8): 123377
Published online Aug 27, 2026. doi: 10.4254/wjh.123377

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Figure 4 Schematic illustration of the pathogenesis underlying the development of the main clinical and laboratory manifestations in primary sclerosing cholangitis. PSC: Primary sclerosing cholangitis; PBGs: Peribiliary glands; Hh: Hedgehog; GP2: Glycoprotein 2; IgA: Immunoglobulin A; pANCA: Perinuclear antineutrophil cytoplasmic antibodies; ANCA: Antineutrophil cytoplasmic antibodies.

Citation: Reshetnyak VI, Reshetnyak AA, Maev IV. Peribiliary and colonic crypt glands in primary sclerosing cholangitis and inflammatory bowel disease pathogenesis: New research perspectives. World J Hepatol 2026; 18(8): 123377
URL: https://www.wjgnet.com/1948-5182/full/v18/i8/123377.htm
DOI: https://dx.doi.org/10.4254/wjh.123377

Reshetnyak VI, Reshetnyak AA, Maev IV. Peribiliary and colonic crypt glands in primary sclerosing cholangitis and inflammatory bowel disease pathogenesis: New research perspectives. World J Hepatol 2026; 18(8): 123377 [DOI: 10.4254/wjh.123377]

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