Clinicopathological characteristics and risk factors in nonalcoholic steatohepatitis patients with different stages of liver fibrosis

doi:10.4254/wjh.121661

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World Journal of Hepatology

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1948-5182

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Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Hepatol. Jul 27, 2026; 18(7): 121661
Published online Jul 27, 2026. doi: 10.4254/wjh.121661

Table 4 Comparison of histological features

Variable	Total (n = 122)	Stage F1 (n = 21)	Stage F2 (n = 86)	Stage F3 (n = 15)	P value
Steatosis, n					0.035^a
Grade 1	11	2	9	0
Grade 2	55	15	34	6
Grade 3	56	4	43	9
Lobular inflammation, n					< 0.001^b^,^c
Grade 1	27	10	16	1
Grade 2	87	11	66	10
Grade 3	8	0	4	4
Ballooning degeneration, n					0.223
Grade 1	41	5	33	3
Grade 2	81	16	53	12

^aP = 0.049 stage F3 vs stage F1 group.

^bP = 0.0018 stage F2 vs stage F1 group.

^cP < 0.001 stage F3 vs stage F1 group.

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Citation: Pan PY, Zheng WW, Guo YQ, Liu YG, Zhang XJ, Wu YY, Li JZ, Qi JG, Wang CY. Clinicopathological characteristics and risk factors in nonalcoholic steatohepatitis patients with different stages of liver fibrosis. World J Hepatol 2026; 18(7): 121661
URL: https://www.wjgnet.com/1948-5182/full/v18/i7/121661.htm
DOI: https://dx.doi.org/10.4254/wjh.121661

Pan PY, Zheng WW, Guo YQ, Liu YG, Zhang XJ, Wu YY, Li JZ, Qi JG, Wang CY. Clinicopathological characteristics and risk factors in nonalcoholic steatohepatitis patients with different stages of liver fibrosis. World J Hepatol 2026; 18(7): 121661 [DOI: 10.4254/wjh.121661]

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