Plasma exosomal miR-137 activates natural killer cells in primary biliary cholangitis by targeting NFATC1

Figure 4 Expression levels of candidate miRNAs in natural killer cells from patients with primary biliary cholangitis and healthy controls. A: Expression levels of 10 predicted microRNAs (miRNAs) in natural killer (NK) cells isolated from patients with primary biliary cholangitis (PBC) and healthy controls (HCs) were measured by quantitative polymerase chain reaction; B: Ct values of miR-137-3p (P = 0.0053), miR-124-3p (P = 0.0034), miR-506-3p (P = 0.0010), and other miRNAs are shown. Higher Ct values indicate lower miRNA expression. The Ct values for miR-137-3p, miR-124-3p, and miR-506-3p were significantly higher in patients with PBC compared to HC, indicating their lower expression in PBC natural killer cells.