Copyright: ©Author(s) 2026.
World J Hepatol. May 27, 2026; 18(5): 119798
Published online May 27, 2026. doi: 10.4254/wjh.v18.i5.119798
Published online May 27, 2026. doi: 10.4254/wjh.v18.i5.119798
Table 3 Performance of machine learning and deep learning models with 26 features and liver stiffness-platelet ratio index + 26 features on imbalanced dataset
| Models | Area under the receiver operating characteristic curve | Youden | Positive predictive value (%) | Negative predictive value (%) | Accuracy (%) | True positives (n) | False positive (n) | True negative (n) | False negative (n) | Sensitivity (%) | Specificity (%) |
| Using 26 features | |||||||||||
| LogisticRegression | 0.85 | 0.58 | 0.57 | 0.92 | 0.80 | 41.40 | 31.60 | 134.00 | 12.40 | 0.77 | 0.81 |
| SVM | 0.83 | 0.55 | 0.55 | 0.91 | 0.79 | 40.40 | 33.40 | 132.20 | 13.40 | 0.75 | 0.80 |
| NuSVC | 0.81 | 0.52 | 0.51 | 0.91 | 0.76 | 41.40 | 40.80 | 124.80 | 12.40 | 0.77 | 0.75 |
| DecisionTree | 0.70 | 0.40 | 0.54 | 0.85 | 0.77 | 29.80 | 25.60 | 140.00 | 24.00 | 0.55 | 0.85 |
| ExtraTree | 0.63 | 0.27 | 0.44 | 0.82 | 0.72 | 24.80 | 32.00 | 133.60 | 29.00 | 0.46 | 0.81 |
| GaussianNB | 0.80 | 0.49 | 0.52 | 0.89 | 0.77 | 38.20 | 35.80 | 129.80 | 15.60 | 0.71 | 0.78 |
| GradientBoosting | 0.88 | 0.63 | 0.60 | 0.93 | 0.82 | 43.20 | 29.00 | 136.60 | 10.60 | 0.80 | 0.82 |
| HistGradientBoosting | 0.87 | 0.62 | 0.55 | 0.94 | 0.79 | 45.20 | 37.00 | 128.60 | 8.60 | 0.84 | 0.78 |
| AdaBoost | 0.86 | 0.61 | 0.54 | 0.95 | 0.78 | 46.20 | 41.60 | 124.00 | 7.60 | 0.86 | 0.75 |
| RandomForest | 0.87 | 0.62 | 0.58 | 0.93 | 0.81 | 44.00 | 32.00 | 133.60 | 9.80 | 0.82 | 0.81 |
| KNeighbors | 0.77 | 0.43 | 0.47 | 0.89 | 0.72 | 38.00 | 46.40 | 119.20 | 15.80 | 0.71 | 0.72 |
| KAN | 0.83 | 0.55 | 0.56 | 0.91 | 0.79 | 40.80 | 34.20 | 131.40 | 13.00 | 0.76 | 0.79 |
| NeuralNetwork | 0.84 | 0.57 | 0.55 | 0.92 | 0.78 | 42.80 | 36.80 | 128.80 | 11.00 | 0.80 | 0.78 |
| Using liver stiffness-platelet ratio index + 26 features | |||||||||||
| LogisticRegression | 0.85 | 0.58 | 0.58 | 0.91 | 0.81 | 40.80 | 29.00 | 136.60 | 13.00 | 0.76 | 0.82 |
| SVM | 0.83 | 0.55 | 0.54 | 0.91 | 0.78 | 41.00 | 34.80 | 130.80 | 12.80 | 0.76 | 0.79 |
| NuSVC | 0.81 | 0.53 | 0.54 | 0.91 | 0.77 | 40.40 | 37.20 | 128.40 | 13.40 | 0.75 | 0.78 |
| DecisionTree | 0.67 | 0.35 | 0.51 | 0.84 | 0.76 | 26.80 | 25.00 | 140.60 | 27.00 | 0.50 | 0.85 |
| ExtraTree | 0.66 | 0.32 | 0.48 | 0.83 | 0.75 | 26.40 | 28.40 | 137.20 | 27.40 | 0.49 | 0.83 |
| GaussianNB | 0.81 | 0.52 | 0.58 | 0.89 | 0.80 | 37.20 | 27.80 | 137.80 | 16.60 | 0.69 | 0.83 |
| GradientBoosting | 0.87 | 0.62 | 0.56 | 0.94 | 0.80 | 44.80 | 34.80 | 130.80 | 9.00 | 0.83 | 0.79 |
| HistGradientBoosting | 0.87 | 0.61 | 0.53 | 0.94 | 0.78 | 46.00 | 41.40 | 124.20 | 7.80 | 0.86 | 0.75 |
| AdaBoost | 0.85 | 0.58 | 0.59 | 0.92 | 0.80 | 42.00 | 33.00 | 132.60 | 11.80 | 0.78 | 0.80 |
| RandomForest | 0.86 | 0.64 | 0.62 | 0.93 | 0.82 | 43.60 | 28.80 | 136.80 | 10.20 | 0.81 | 0.83 |
| KNeighbors | 0.78 | 0.42 | 0.47 | 0.88 | 0.72 | 37.00 | 44.20 | 121.40 | 16.80 | 0.69 | 0.73 |
| KAN | 0.84 | 0.58 | 0.55 | 0.92 | 0.79 | 42.60 | 35.80 | 129.80 | 11.20 | 0.79 | 0.78 |
| NeuralNetwork | 0.85 | 0.59 | 0.59 | 0.92 | 0.81 | 41.00 | 28.80 | 136.80 | 12.80 | 0.76 | 0.83 |
- Citation: Lin JY, Ai ZX, Luo MJ, Su LZ, Gao XG, Jiang HL, Lin JQ, Zhang HY, Sun YY, Yu HT, Zhang L, Gong XQ. Liver stiffness-platelet ratio index and machine learning models for the noninvasive diagnosis of significant fibrosis in chronic hepatitis B. World J Hepatol 2026; 18(5): 119798
- URL: https://www.wjgnet.com/1948-5182/full/v18/i5/119798.htm
- DOI: https://dx.doi.org/10.4254/wjh.v18.i5.119798