Diagnostic and prognostic utility of serum bile acid in liver transplant recipients: A systematic review and quantitative synthesis

Table 1 Study characteristics

Ref.	Country	Study population	Population characteristics			Timing of the SBA measurement	The SBA measurement method	Reported outcomes
			Sample size	Male/female	Age
Azer et al[9]	Australia	Adult patients who underwent OLT	8	1/7	49.63 years	Daily post-transplant measurements (every 6 hours for the first 2 days and then every 24 hour for the following 12 days)	NR	Graft dysfunction and acute graft rejection
Janssen et al[10]	Germany	Adult patients who underwent OLT	41	NR	Patients without acute rejection: 50 years of age. Patients with acute rejection: 42 years	Daily post-transplant measurements	The enzymatic photometric method	Acute graft rejection
Sundararajan et al[11]	India	Patients who underwent LDLT	63	NR	NR	Preoperative and postoperative data from day 1 to day 14	NR	Graft dysfunction and acute graft rejection
Muraca et al[12]	Germany	Adult patients who underwent OLT	20	NR	NR	Postoperatively	Enzymatic fluorimetric assay method	Graft rejection
Wu et al[14]	Taiwan	Pediatric patients who underwent LDLT	60	24/36	2.04 years	Postoperatively	Enzymatic assay method	Biliary stricture and patient survival

NR: Not reported; OLT: Orthotopic liver transplant; LDLT: Living donor liver transplant; SBA: Serum bile acid.