Ten-year enzyme replacement therapy in early childhood-onset lysosomal acid lipase deficiency: A case report

Table 2 Evaluation of liver and spleen size and lipid content by abdominal magnetic resonance imaging

Parameter	Evaluation time	Absolute value (multiples of normal)	Change from baseline	% change from baseline
Hepatic volume	First visit	1.79
	Week 48	1.30	-0.48	-27.1
	Week 96	1.41	-0.37	-20.9
Hepatic lipid content	First visit	7.52
	Week 48	6.62	-0.9	-12.0
	Week 96	7.77	0.25	3.3
Splenic volume	First visit	2.24
	Week 48	2.73	0.49	21.9
	Week 96	2.16	-0.08	-3.7
Splenic lipid content	First visit	1.41
	Week 48	2.23	0.24	12.1
	Week 96	1.37	-0.62	-31.2