Differentiation of minimal and grade 1 hepatic encephalopathy using neurophysiological, neuropsychological, magnetic resonance spectroscopic, and systemic inflammatory parameters

doi:10.4254/wjh.v18.i5.118040

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World Journal of Hepatology

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1948-5182

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World J Hepatol. May 27, 2026; 18(5): 118040
Published online May 27, 2026. doi: 10.4254/wjh.v18.i5.118040

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Figure 3 Receiver operating characteristic curves of Bispectral index, mean dominant frequency, relative powers of electroencephalogram frequencies, and magnetic resonance spectroscopy peak values in predicting minimal hepatic encephalopathy. A: Bispectral index [area under the receiver operating characteristic (AUROC: 0.911)], mean dominant frequency (AUROC: 0.876), beta (AUROC: 0.876), alpha (AUROC: 0.876), delta (AUROC: 0.876), theta (AUROC: 0.886), myoinositol (AUROC: 0.911), choline (AUROC: 0.876), glutamine (AUROC: 0.886); B: Grade 1 hepatic encephalopathy [Bispectral index (AUROC: 0.911)], mean dominant frequency (AUROC: 0.876), beta (AUROC: 0.876), alpha (AUROC: 0.876), delta (AUROC: 0.876), theta (AUROC: 0.886), myoinositol (AUROC: 0.739), choline (AUROC: 0.681), glutamine (AUROC: 0.741). BIS: Bispectral index; MDF: Mean dominant frequency.

Citation: Kummetha LC, Bhatt S, Vaithiyam V, Sharma BC, Srivastava S, Mahajan B, Bansal K, Chaudhry N, Tandon MS, Sachdeva S, Kumar A, Dalal A, Sonika U. Differentiation of minimal and grade 1 hepatic encephalopathy using neurophysiological, neuropsychological, magnetic resonance spectroscopic, and systemic inflammatory parameters. World J Hepatol 2026; 18(5): 118040
URL: https://www.wjgnet.com/1948-5182/full/v18/i5/118040.htm
DOI: https://dx.doi.org/10.4254/wjh.v18.i5.118040

Kummetha LC, Bhatt S, Vaithiyam V, Sharma BC, Srivastava S, Mahajan B, Bansal K, Chaudhry N, Tandon MS, Sachdeva S, Kumar A, Dalal A, Sonika U. Differentiation of minimal and grade 1 hepatic encephalopathy using neurophysiological, neuropsychological, magnetic resonance spectroscopic, and systemic inflammatory parameters. World J Hepatol 2026; 18(5): 118040 [DOI: 10.4254/wjh.v18.i5.118040]

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