Differentiation of minimal and grade 1 hepatic encephalopathy using neurophysiological, neuropsychological, magnetic resonance spectroscopic, and systemic inflammatory parameters

doi:10.4254/wjh.v18.i5.118040

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World Journal of Hepatology

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1948-5182

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World J Hepatol. May 27, 2026; 18(5): 118040
Published online May 27, 2026. doi: 10.4254/wjh.v18.i5.118040

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Figure 2 Receiver operating characteristic curves of inflammatory markers for predicting minimal hepatic encephalopathy. A: Tumor necrosis factor-alpha [area under the receiver operating characteristic (AUROC): 0.934], interleukin-6 (IL-6) (AUROC: 0.864), IL-18 (AUROC: 0.962), endotoxin (AUROC: 0.976), IL-10 (AUROC: 0.976), IL-12 (AUROC: 0.984), IL-1β (AUROC: 0.993); B: Grade 1 hepatic encephalopathy [tumor necrosis factor-alpha (AUROC: 0.729)], IL-6 (AUROC: 0.751), IL-18 (AUROC: 0.812), endotoxin (AUROC: 0.989), IL-10 (AUROC: 0.833), IL-12 (AUROC: 0.921), IL-1β (AUROC: 0.938). TNF-α: Tumor necrosis factor-alpha; IL: Interleukin.

Citation: Kummetha LC, Bhatt S, Vaithiyam V, Sharma BC, Srivastava S, Mahajan B, Bansal K, Chaudhry N, Tandon MS, Sachdeva S, Kumar A, Dalal A, Sonika U. Differentiation of minimal and grade 1 hepatic encephalopathy using neurophysiological, neuropsychological, magnetic resonance spectroscopic, and systemic inflammatory parameters. World J Hepatol 2026; 18(5): 118040
URL: https://www.wjgnet.com/1948-5182/full/v18/i5/118040.htm
DOI: https://dx.doi.org/10.4254/wjh.v18.i5.118040

Kummetha LC, Bhatt S, Vaithiyam V, Sharma BC, Srivastava S, Mahajan B, Bansal K, Chaudhry N, Tandon MS, Sachdeva S, Kumar A, Dalal A, Sonika U. Differentiation of minimal and grade 1 hepatic encephalopathy using neurophysiological, neuropsychological, magnetic resonance spectroscopic, and systemic inflammatory parameters. World J Hepatol 2026; 18(5): 118040 [DOI: 10.4254/wjh.v18.i5.118040]

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