Association between overt, subclinical hypothyroidism and metabolic dysfunction-associated steatotic liver disease using magnetic resonance imaging

Table 5 Laboratory characteristics of metabolic dysfunction-associated steatotic liver disease and non-metabolic dysfunction-associated steatoic liver disease groups, mean ± SD

Variable	MASLD	Non-MASLD	P value
ALT (U/L)	30.3 ± 56.5	20.3 ± 10.1	0.123
AST (U/L)	27.2 ±29.6	20.5 ± 7.6	0.054
TSH (mIU/L)	22.9 ± 26.4	4.1 ± 3	< 0.001
FT4 (ng/dL)	1 ± 0.3	1.2 ± 0.2	< 0.001
Total cholesterol (mg/dL)	191.8 ± 40.2	168.4 ± 39.4	< 0.001
High density lipoprotein (mg/dL)	48.7 ± 11.6	48.4 ± 17.1	0.892
Low density lipoprotein (mg/dL)	118.3 ± 32.1	102.4 ± 39.3	0.009
Triglycerides (mg/dL, median (range)	106 (33-356)	76 (31-344)	< 0.001

P value < 0.05 is considered significant. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; FT4: Free thyroxine; TSH: Thyroid-stimulating hormone; MASLD: Moderate metabolic dysfunction-associated steatotic liver disease.