Association between overt, subclinical hypothyroidism and metabolic dysfunction-associated steatotic liver disease using magnetic resonance imaging

doi:10.4254/wjh.v18.i5.117441

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World Journal of Hepatology

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1948-5182

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Hepatol. May 27, 2026; 18(5): 117441
Published online May 27, 2026. doi: 10.4254/wjh.v18.i5.117441

Table 3 Prevalence of metabolic dysfunction-associated steatotic liver disease among the three study groups, n (%)

Variable	Overt hypothyroidism (A) (n = 48)	Subclinical hypothyroidism (B) (n = 48)	Control (C) (n = 48)	P value	Paire-wise comparison
MASLD by ultrasound
Non-MASLD	13 (27.1)	21 (43.8)	45 (93.8)	< 0.001	A vs B: 0.135
MASLD	35 (72.9)	27 (56.3)	3 (6.3)		A vs C: < 0.001
MASLD	35 (72.9)	27 (56.3)	3 (6.3)		B vs C: < 0.001
MASLD by MRI
Non-MASLD	14 (29.2)	21 (43.8)	45 (93.8)	< 0.001	A vs B: 0.203
MASLD	34 (70.8)	27 (56.3)	3 (6.3)		A vs C: < 0.001
MASLD	34 (70.8)	27 (56.3)	3 (6.3)		B vs C: < 0.001

MASLD: Metabolic dysfunction-associated steatotic liver disease; MRI: Magnetic resonance imaging.

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Citation: Sholkamy A, El-Meligui A, H Saad E, Amin S, Makram M, Elmansy N, Mousa S. Association between overt, subclinical hypothyroidism and metabolic dysfunction-associated steatotic liver disease using magnetic resonance imaging. World J Hepatol 2026; 18(5): 117441
URL: https://www.wjgnet.com/1948-5182/full/v18/i5/117441.htm
DOI: https://dx.doi.org/10.4254/wjh.v18.i5.117441

Sholkamy A, El-Meligui A, H Saad E, Amin S, Makram M, Elmansy N, Mousa S. Association between overt, subclinical hypothyroidism and metabolic dysfunction-associated steatotic liver disease using magnetic resonance imaging. World J Hepatol 2026; 18(5): 117441 [DOI: 10.4254/wjh.v18.i5.117441]

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