Congenital porto-sinusoidal vascular disorder-induced portal hypertension: A comprehensive review based on a classic clinical case

doi:10.4254/wjh.v18.i5.117184

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Hepatol. May 27, 2026; 18(5): 117184
Published online May 27, 2026. doi: 10.4254/wjh.v18.i5.117184

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Figure 1 Occlusive portal vein lesions accompanied by nodular regenerative hyperplastic changes. A: Hepatic sinusoidal lymphocytic infiltration and stromal fibrosis in the confluent zone of the portal vein; B: Portal vein was partially narrowed and occluded, partially tortuous and dilated; C: Peri-sinusoid fibrosis (Masson trichrome); D: Nodular disorganization with hepatocyte plate atrophy (reticulin); E: Immunohistochemical staining showed positivity for CD10, CD38, CK19, and CK7. Scale bars = 100 μm.

Citation: Xu MJ, Wei X, Huang Y, Lu Y, Sun L, Xie Y, Li MH. Congenital porto-sinusoidal vascular disorder-induced portal hypertension: A comprehensive review based on a classic clinical case. World J Hepatol 2026; 18(5): 117184
URL: https://www.wjgnet.com/1948-5182/full/v18/i5/117184.htm
DOI: https://dx.doi.org/10.4254/wjh.v18.i5.117184

Xu MJ, Wei X, Huang Y, Lu Y, Sun L, Xie Y, Li MH. Congenital porto-sinusoidal vascular disorder-induced portal hypertension: A comprehensive review based on a classic clinical case. World J Hepatol 2026; 18(5): 117184 [DOI: 10.4254/wjh.v18.i5.117184]

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