Navigating the therapeutic tightrope: Precision use of plasmapheresis and continuous renal replacement therapy in liver failure

Figure 1 Illustration of therapeutic plasma exchange using centrifugation and membrane techniques. In the centrifugation process, blood is extracted from the patient, treated with an anticoagulant, and separated into plasma, which is then substituted with a replacement fluid before being returned. The membrane technique involves pumping blood through a unique fibre filter to isolate plasma, followed by reinfusion with a substitute solution. TPE: Therapeutic plasma exchange.