Diagnostic accuracy of blood-based non-invasive tests for prediction of varices in pediatric portal-hypertension: A systematic review and meta-analysis

Figure 5 Summary diagnostic accuracy of non-invasive indices for clinically significant varices prediction. A: Forest plot for sensitivity, specificity, and hierarchical summary receiver operating characteristic (HSROC) plot of clinical prediction rule; B: Forest plot for sensitivity, specificity, and HSROC plot of varices prediction rule; C: Forest plot for sensitivity, specificity, and HSROC plot of King’s variceal prediction score. In the HSROC plot, each study is identified with a small black circle. Square denotes the combined sensitivity and specificity, grey shaded area is the 95% confidence region, and the dashed line is the 95% prediction region.