Correlation between non-alcoholic fatty liver disease and erectile dysfunction: A systematic narrative review

Table 3 Factors influencing the development of erectile dysfunction in non-alcoholic fatty liver disease patients

Ref.	Influencing factors	Conclusions
Tarik Kani et al[3], 2021	Age, obesity, hypertension	Older age, obesity, and hypertension are associated with ED in the NAFLD cohort
Youcheng et al[10], 2025	US-FLI	NAFLD is positively correlated with ED
Duman et al[11], 2016	NAFLD score	There is a significant association between NAFLD and ED
Yilmaz et al[12], 2021	Age, MetS, NAFLD score	As NAFLD-related liver damage progresses, symptoms of ED show a significant worsening trend
Eren and Horsanali[13], 2019	Age, MetS, NAFLD score	The higher the NAFLD grade, the lower the IIEF-5 score
Hasanain et al[14], 2017	Age ≥ 40 years, IR, low serum testosterone	Age, insulin resistance, and low serum testosterone levels are independently associated with ED
Ragab et al[15], 2024	Serum adropin, creatinine, GAD-7 score	GAD-7 scale scores, creatinine levels, and adropin were the only strong independent predictors of IIEF-5 scores

US-FLI: Ultrasonographic fatty liver indicator; NAFLD: Non-alcoholic fatty liver disease; ED: Erectile dysfunction; MetS: Metabolic syndrome; IR: Insulin resistance; GAD-7: Generalized anxiety disorder-7; IIEF-5: Five-item version of the International Index of Erectile Function.